Statistical software for gene mapping by admixture linkage disequilibrium
نویسندگان
چکیده
منابع مشابه
Statistical software for gene mapping by admixture linkage disequilibrium
Admixture mapping is a statistical methodology that detects genetic variants in recently admixed populations that are responsible for ethnic differences in disease risk. Three software packages are now available for admixture mapping and we provide a brief overview of the statistical methods and other principal features they implement.
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Mapping by admixture linkage disequilibrium (MALD) is a potentially powerful technique for the mapping of complex genetic diseases. The practical requirements of this method include (a) a set of markers spanning the genome that have large allele-frequency differences between the parental ethnicities contributing to the admixed population and (b) an understanding of the extent of admixture in th...
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ژورنال
عنوان ژورنال: Briefings in Bioinformatics
سال: 2007
ISSN: 1467-5463,1477-4054
DOI: 10.1093/bib/bbm035